Sexual dysfunction and motor disability in Parkinson’s disease: any link?
نویسندگان
چکیده
Introduction Parkinson’s disease (PD) is a chronic, neurodegenerative disorder leading to dopamine deficiency. Phenotypically, there wide spectrum of motor and non-motor symptoms (NMS). Among NMS, sexual dysfunction (SD) one the most disabling crippling symptom. However, SD are usually neglected underdiagnosed in PD patients. Objectives Our study aimed estimate effect disability course on Methods This retrospective included 42 patients (18 males 24 females) from department neurology National Institute Neurology Mongi Ben Hmida Tunis, Tunisia, diagnosed with between 1999 2022. The diagnosis was confirmed according Movement Disorder Society (MDS) diagnostic criteria PD. MDS Unified Disease Rating Scale (MDS-UPDRS) used Hoehn Yahr (H&Y) stage rate severity. measured by applying items Scales for Outcomes - Autonomic Dysfunction (SCOPA-AUT). Results observed only 11 (26.2%) sex-ratio M/F = 1.2 mean age 52 (between 40 72). onset 47. According MDS-UPDRS part III, 1 patient had severe (MDS-UPDRS> 59), H&Y scale, no disease. Nine complications such as fluctuations L-Dopa induced dyskinesia. described our were: women reported Vaginal Dryness (4 patients), difficulties reaching an orgasm (3 patients); men erectile (6 patients). these patients, 3 were treated Tadalafil (all males). In study, significant gender-related differences found scores related Neither severity nor significantly associated disorders (respectively p=0.26 p=0.12). Also, Motor medication, assessed IV occurrence (p=0.78). Conclusions Sexual behavior has neuronal hormonal modulation. Lack seems have important role development SD. it occurs independently disability. Thus, clinicians should be aware importance assessing treating since beginning Disclosure Interest None Declared
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ژورنال
عنوان ژورنال: European Psychiatry
سال: 2023
ISSN: ['0924-9338', '1778-3585']
DOI: https://doi.org/10.1192/j.eurpsy.2023.2327